When it comes to soundness, horse owners will often try to make informed decisions about joint supplements, even if their efficacy is difficult to prove.
“Products marketed for joint health are among the most popular equine nutritional supplements despite the fact that efficacy evidence of most commercially available products is lacking,” noted Kathleen Crandell, Ph.D., an equine nutritionist for Kentucky Equine Research (KER).
Typical ingredients found in oral joint health supplements include one or more of the following:
1.Glucosamine (hydrochloride or sulfate);
2.Chondroitin sulfate;
3.Methylsulfonylmethane (MSM);
4.Collagen;
5.Hyaluronic acid (HA);
6.Omega-3 fatty acids;
7.Avocado-soybean unsaponifiables (ASU);
8.Curcumin; and
9.Perna mussels.
In a recently published study* looking at the protective effects of oral joint health supplements, researchers used Standardbred horses and administered either a liquid, multi-ingredient joint supplement, a collagen-based supplement, meloxicam (a nonsteroidal anti-inflammatory drug similar to phenylbutazone), or a placebo for 28 to 60 days prior to the challenge. Joint inflammation, known as synovitis, was induced in one carpal joint of each horse. Lameness and select markers of cartilage breakdown and inflammation in synovial fluid were subsequently analyzed.