Figure 1. Mesotrione is more effective when applied under cooler temperatures (photo on left). Source: Mithila Jugulam, K-State Research and Extension.
The research described two key changes in Palmer amaranth that cause reduced control. First, Palmer amaranth metabolized mesotrione faster at higher temperatures. This means the herbicide gets degraded faster when temperatures are high, making the herbicide less effective. Second, the HPPD enzyme, which is the target site for Group 27 herbicides, had increased activity at high temperatures, making it easier for the plant to overcome the effects of mesotrione.
For maximum effectiveness, Group 27 herbicides should be applied under the coolest conditions possible. It is very likely that other pigweed species such as waterhemp and other Group 27 herbicides, including tembotrione (Laudis), tolpyralate (Shieldex), topramezone (Impact), Balance Flexx (isoxaflutole), and pyrasulfatole (Huskie) will react the same way as Palmer amaranth to mesotrione.
Source : ksu.edu